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Compulsory sterilization laws adopted by over 30 states led to more than 60,000 sterilizations of disabled individuals. Many of these individuals were sterilized because of a disability: they were mentally disabled or ill, or belonged to socially disadvantaged groups living on the margins of society.

The U.S. Supreme Court ruled (8-1) that laws mandating the sterilization of the mentally handicapped do not violate the Constitution in the case Buck v. Bell.

The practice of female sterilization in a California prison during a period of four years (2006-2010). At least 148 women at the California Institution for Women in Corona and Valley State Prison for Women in Chowchilla were permanent sterilized.

DIY gender reassignment surgery is not recommended.